Episodes

It’s our 50th episode! To celebrate this, Asif asks Ali about his top 3 favorite comedy specials (1:31). Ali picks Dave Chapelle’s ‘Killing Them Softly’, Wanda Sykes’ Im’a Be Me’ and Eddie Izzard’s ‘Dress to Kill’ and discusses what makes these specials so good. Then Ali asks Asif about the biological basis of why we develop laughter (32:04). Asif goes over how laughter and humour develops in babies and what they find ‘funny’. Then, Asif talks about the areas of the brain where laughter originat...

To start the episode, Ali asks Asif about 2 movies he saw recently - Spider-Man: No Way Home and The Matrix Resurrections. Short story: one was good nostalgia and the other reminded him of the “member berries” from South Park. Then, Asif asks Ali about how comedians create personas for comedy (7:28). Ali also discusses how podcasts and twitter have made personas less common but also discusses the advantages of using a persona. The guys then discuss some classic comedians who have used personas s...

Today on a very special episode, Ali and Asif interview superstar podcaster Dr. Sydnee McElroy (Sawbones, Still Buffering). In their wide ranging conversation they discuss how she got started in podcasting with her husband, Justin McElroy, and how they developed the wildly successful podcast ‘Sawbones’. Then they discuss the evolution of her other podcast ‘Still Buffering’ which she co-hosts with her sisters. Later, they discuss her volunteer work with the homeless population in her city, physi...

The guys start out discussing the recent snowstorms in North America, the politeness (or lack thereof) of Torontonians, Ali’s toothache and leaving your phone number with bakeries. Then the guys discuss the recent deaths of Louie Anderson and Bob Saget. They start by discussing the legendary Louie Anderson (5:40) his acting on shows such as ‘Baskets’ and his legacy in comedy. The guys then discuss Bob Saget, his television work and the contrast to his outrageous stand up personality (17:48). Th...

Today on a special episode, the guys discuss the case of Mike Ward, who was accused of breaching the limits of free speech when he mocked a disabled singer named Jeremy Gabriel (“Petit Jeremy")...a case that went all the way up to the Supreme Court of Canada. They are joined by their special guest comedian and lawyer Jess Salomon (The Tonight Show, Comedians vs The News). After briefly chatting about Jess’ experiences with the Omicron variant, Jess and Ali disclose that they do know Mike Ward pe...

To start the episode, Ali talks about his new CBC show out now “Run the Burbs” and Ali’s appearance on “Family Feud Canada”. Betty White would have been 100 years old on Jan 17, 2022, so to commemorate this, the guys go over her life and career (7:36). They discuss her roles in “The Mary Tyler Moore Show”, “The Golden Girls” and her devotion to civil rights and animal charities. Then Ali asks Asif about Electronic Medical Records (EMR’s) by using Atul Gawande’s 2018 New Yorker article on the top...

Today, Ali and Asif discuss the career of the great Kal Penn (1:46). They discuss his early career all the way up to the release of his memoir, ‘You Can’t Be Serious”. They discuss his famous roles in ‘American Desi’, ‘Harold and Kumar Go to White Castle’, ‘Van Wilder’, ‘The Namesake’, ‘House’ and ‘Designated Survivor’. They discuss Kal coming out as gay as well as his recent engagement. Then Ali asks Asif about Physician Burnout (33:01). Asif starts out by defining physician burnout and discus...

As a year-end treat, the guys go over their favourite entertainment from 2021… and decide to omit the big 2021 medical topic, since people are likely tired of talking about the Covid-19 pandemic. Ali starts off by talking about his favourite books he read last year (1:44). Then Asif discusses new music he got into in 2021. The guys then compare notes on their favourite movies of 2021 and disagree intensely about Wes Anderson and ‘The French Dispatch’. Then the guys discuss their thoughts on bes...

Today, Ali and Asif each list their top albums from one of the greatest years for music, 1991 (2:01). The guys go over their top albums, their honourable mentions and their lowlights of that year. Then, Ali asks Asif why the music from our youth connects so much with us (47:59). Asif discusses the research by Daniel Levitin on music and the brain and discusses why the songs from when we are young are “burned into our brains”. Asif then goes over the sociological reasons why we remember certain l...

In response to a listener's question, the guys attempt to answer the questions: “What does it mean to be funny?” and “What does it mean to be healthy?”. After a brief digression about humour in rats, Ali discusses how ‘funny’ laughter and active listening are intricately linked (2:21). He outlines the 4 major concepts that people find amusement in: 1) the misfortunes of others; 2) expressions of otherwise forbidden emotions; 3) juxtaposition of incompatible concepts; 4) realizing that certain ex...

The guys start off this episode with Asif reviewing Shang-Chi and the Legend of the Ten Rings (2:40). Then Asif asks Ali about his thoughts on Larry David, ‘Curb Your Enthusiasm’ and cringe comedy (12:16). Ali talks about the influence of Ricky Gervais ( The Office ) and Sacha Baron Cohen ( Da Ali G Show ) on cringe comedy. After an aside about the new Willow TV show, the guys talk about Larry David and why he is shocked that ‘Curb’ makes people cringe. They guys then talk about their favourite ...

The guys start off the episode with Asif discussing the problems faced by men after trying on their suits after 18 months of the Covid-19 pandemic (1:18). The guys then compare two albums released in the fall of 1991, Soundgarden’s ‘Badmotorfinger’ and U2’s ‘Achtung Baby’ (3:15). They start off by discussing ‘Badmotorfinger’ and the amazing productivity of Chris Cornell in the fall 1991 and the overall innovation of the album. The guys then discuss U2’s ‘Achtung Baby’; they discuss the tensions ...

The guys start off the episodes by discussing Ali’s recent attendance at a Toronto Maple Leafs game and his ‘Sophie’s Choice’ of needing to choose whether to cheer for Toronto or the Boston Bruins (1:40). Asif then discusses his thoughts on the recent movie by Denis Villeneuve ‘Dune”. Then Asif asks Ali about Kumail Nanjiani and his thoughts on his body transformation and the reasons Kumail has given about his reasons for getting into shape (9:42). They then talk about Kumail posting pics of his...

Today, the guys switch things around by discussing the medical topic first -- Tics and Tourette Syndrome (1:02). Asif discusses what the symptoms of Tourette Syndrome are, how you diagnose it and what causes it. He also talks about other commonly associated conditions and why you often do NOT need to treat tics. Then Ali and Asif discuss Tourette Syndrome on tv shows, movies and especially social media (20:50). Asif discusses how he was asked to be on the TV show “Employable Me” as a medical exp...

On today’s episode, after a brief discussion of Jerry Seinfeld’s “Is this Anything?”, Ali discusses how he and other comedians come up with material (2:21). He talks about writing out jokes, practicing them at open mics and refining them over time. He then talks about what happens when you recommend a joke to a comic. Then, Asif discusses the health benefits of laughter on pain tolerance, interpersonal relationships and stress (29:17). He then discusses ‘laughter yoga’ and whether there is evid...

Today, in honour of the 30th anniversary of the release of Guns N’ Roses’ ‘Use Your Illusion 1 and 2’ and Metallica’s ‘Black Album’, the guys debate which album is better (and yes, we know UYI is 2 albums -- we’re counting them as one…) (1:41). Ali starts off by recounting the story of how he attended the infamous Metallica/Guns N’ Roses concert in the summer of 1992, which resulted in a massive riot in downtown Montreal. The guys discuss how big GNR were in the early nineties and recount how ...

Today, the guys discuss the hit Netflix Show ‘Squid Game’ (1:13) and the influence of Korea on popular culture (BTS, ‘Parasite’) . They talk about how it was developed by writer/director Hwang Dong-hyuk , Netflix and Ted Sarandos. They discuss how it became a global phenomenon and how it’s ‘The Prisoner’ and ‘The Hunger Games’. They mention the excellent acting by Lee Jung-jae, Kim Joo-ryoung and Anupam Tripathi . Ali points out the stress of Hwang being a writer-director on every episode and he...

Today, Asif asks Ali about the controversial origins of stand up comedy (1:05). Ali explains that stand up comedy evolved from vaudeville and that vaudeville itself evolved from minstrel shows. With respect to minstrel shows, Ali specifically references Thomas Dartmouth Rice 's blatantly racist song-and-dance number, " Jump Jim Crow ". He also discusses how the Irish were surprisingly often complicit in performing in blackface. Ali then discusses the long term ramifications of the fact that sta...

Today, the guys start off the pod with a bit of banter about ‘banter’. Then, in honour of ‘Seinfeld’ being released on Netflix this month, Asif and Ali discuss their thoughts and memories of the sitcom. Then they both debate their top 5 ‘Seinfeld’ episodes of all time. Then Ali asks Asif about body odour, and the guys use the ‘Seinfeld’ episode “The Smelly Car” as the perfect transition. Ali recounts a story about having to tell someone in one of his classes about their BO. Asif talks about th...

Today, the guys start off the pod by discussing 2 new television shows: Sandra Oh in ‘The Chair’ and FX’s ‘Y: The Last Man’ (0:43). Then Asif asks Ali about what life is really like on television and movie sets (8:53). Ali talks about the first set he was on and how he learned the “rules” of being on set. Ali then talks about the food on sets including craft services and catering as well as trailers on sets. Finally, Ali talks about his star-studded interactions with actors on set such as John L...

Today, the guys start off by discussing the recently departed Norm Macdonald (1:00). They talk about his unique comic voice and the tremendous respect Ali and other comics had for him. Then, since both albums were released 30 years ago this month, the guys debate which album is better: Nirvana’s Nevermind’ or Pearl Jam’s ‘Ten (8:09)’. During their wide-ranging conversation, they reference the origins of the name “Smell’s Like Teen Spirit”, the recent lawsuit filed regarding the photo on the cove...

To start the show, the guys discuss the sometimes murky issue of copyright claims on YouTube (1:30). Then the guys preview the upcoming 73rd annual Emmy awards and their picks in various categories (7:03). Then, Ali asks Asif about the academic publishing and why Asif feels the whole system of academic publishing needs to be fixed (29:39). He discusses the monopoly of academic publishers as well as the problems with the peer review process and so called Open Access. He then discusses the controv...

The guys start with a serious debate about whether ‘drums’ or ‘flats’ are the better chicken wings (00:50). Ali then discusses life on the road as a comedian (5:11), including tips on how to get started in comedy touring. Then, Asif discusses the influence of the pharmaceutical industry on the prescribing habits of doctors (29:36). He discusses his own personal experiences with pharma, as well as what the evidence says about whether the pens, dinners and trips given to doctors actually influence...

In this episode, Ali and Asif discuss the surging rates of eating disorders during the Covid-19 pandemic, with Adolescent Medicine and Eating Disorders expert Dr. Megan Harrison (who also happens to be Asif’s wife). Dr. Harrison discusses what eating disorders are and how adolescents develop them. Dr. Harrison also discusses how eating disorders are occurring in younger and younger children and the effects of restricted eating on the brain. She discusses the risk of mortality in eating disorders...