Remembering Rob Reiner and Catherine O’Hara, plus Situs Inversus

The guys were on hiatus when two prominent entertainers passed away – Rob Reiner and Catherine O’Hara – so today Ali and Asif discuss their careers. They guys start of by discussing Rob Reiner (3:43), his early career and when they both first heard of him. They discuss ‘All in the Family’, 

This is Spinal Tap’, and Rob Reiner’s unprecedented run of movies beginning with ‘Stand By Me’ to ‘A Few Good Men’.  Finally they discuss Reiner’s life outside of entertainment, including his political activism.

Then they discuss Catherine O’Hara’s comedy legacy (19:17). The guys chat about seeing O’Hara originally  in ‘SCTV’, ‘Beetlejuice’ and ‘Home Alone’. Then they talk about her roles in Christopher Guest’s mockumentaries, ‘Schitt’s Creek’, ‘The Last of Us’ and ‘The Studio’. 

O’hara suffered from situs inversus (although she died from complications of rectal cancer), so in the last part of the podcast, Ali asks Asif about this disorder (33:51). He chats about when it was discovered, as well as how most people can live their whole lives without knowing they have it. He then discusses the potential complications as well as its relation to Kartagener syndrome. 

The opinions expressed are those of the hosts, and do not reflect those of any other organizations. This podcast and website represents the opinions of the hosts. The content here should not be taken as medical advice. The content here is for entertainment and informational purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions. 

Music courtesy of Wataboi and 8er41 from Pixabay

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Show Notes:

• Rob Reiner, Actor Who Went on to Direct Classic Films, Dies at 78: https://www.nytimes.com/2025/12/15/movies/rob-reiner-dead.html
• Catherine O’Hara, ‘Home Alone’ and ‘Schitt’s Creek’ Actress, Dies at 71: https://www.nytimes.com/2026/01/30/arts/television/catherine-ohara-dead.html
• Jiminy Glick Interviews Catherine O'Hara: https://www.youtube.com/watch?v=LwlPI9KpkTs
• Situs Inversus Totalis: A Clinical Review: https://pmc.ncbi.nlm.nih.gov/articles/PMC8901252/
• Mitch & Mickey - A Kiss At The End Of The Rainbow: https://www.youtube.com/watch?v=QwLZfPPM7GQ&list=RDQwLZfPPM7GQ&start_radio=1

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