Sept. 4, 2025

Episode 225: Nate Bargatze / Alcohol Withdrawal

Show Notes

Today, Ali and Asif talk about comedian Nate Bargatze (3:03). The guys start off by discussing when they first heard of Bargatze as well as his early life. They then go over his work ethic and the fact that Nate is a “clean comic”. Ali and Asif then discuss Nate auditioning for The Daily Show, his failed ABC pilot, and a potential movie career. They then go over his amazing comedy style and his hilarious George Washington SNL sketch.

Nate Bargatze struggled with alcohol abuse so in the second half, they discuss alcohol withdrawal (30:25). Asif starts off by discussing how common it is and who is at risk for alcohol withdrawal. Asif goes over the criteria for alcohol use disorder and what is going on in the brain during withdrawal. Ali then asks Asif about the different types of severity of alcohol withdrawal. Asif then talks about the short term treatment of withdrawal and medications that can be used to promote abstinence.

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Show Notes:

Comedian Nate Bargatze on Breaking Arena Records, Going Viral From ‘SNL’ & Staying Non-Political: ‘You Don’t Need Me to Add to That’ https://www.billboard.com/culture/events/comedian-nate-bargatze-on-breaking-arena-records-saturday-night-live-and-staying-non-political-1235742263/

The Nicest Man in Stand-Up: https://web.archive.org/web/20210917104340/https://www.theatlantic.com/magazine/archive/2021/10/nate-bargatze-nicest-stand-up/619812/

Nate Bargatze Conquered Comedy. Hollywood is Next: https://www.hollywoodreporter.com/tv/tv-features/nate-bargatze-interview-stand-up-comedy-acting-1236085644/

Alcohol Use: Managing alcohol withdrawal: https://www.camh.ca/en/professionals/treating-conditions-and-disorders/alcohol-use/alcohol-use---treatment/treatment---managing-alcohol-withdrawal

Alcohol Withdrawal Syndrome: https://www.ncbi.nlm.nih.gov/books/NBK441882/

Alcohol Withdrawal Syndrome: Outpatient Management: https://www.aafp.org/pubs/afp/issues/2021/0900/p253.html

Delirium Tremens (DTs) Clinical Presentation: https://emedicine.medscape.com/article/166032-clinical

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